[Frontiers in Bioscience 7, d872-885, April 1, 2002] 872 POSTSYNAPTIC CALCIUM SIGNALING MICRODOMAINS IN NEURONS
نویسندگان
چکیده
1. Abstract 2. Introduction 3. Morphological basis for postsynaptic calcium microdomains: dendritic spines 4. Organization of calcium signaling complexes in dendritic spines 4.1. Mechanisms of calcium influx in spines 4.1.1. Neurotransmitter-gated ion channels: NMDA receptors 4.1.2. Voltage-dependent calcium channel complexes 4.1.3. IP3 receptor complexes 4.2. Mechanisms of calcium removal from spines 4.2.1. Calcium-ATPases 4.2.2. Spine neck calcium diffusion 4.2.3. Cytoplasmic calcium-buffering proteins 5. Supramolecular protein complexes and synaptic regulation 5.1. Multimodal proteins organizing supramolecular complexes 5.2. Calcium microdomains and synaptic regulation 6. Conclusions and perspective 7. Acknowledgments 8. References
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